Probiotics
Enterococcus feacium
bacteria cells
Probiotics are live micro-organisms which, when administered in adequate amounts, confer a health benefit to the host. (FAO/WHO*, 2002). Probiotics can be defined as microbial cells that have a beneficial effect on the health and well-being of the host.1
Probiotics have a positive effect on the health going beyond the nutritional ones commonly known. The two main mechanism of action have been suggested and are summarised as follows: (a) nutritional effect which is characterised by reduction of metabolic reactions that produce toxic substances, stimulation of indigenous enzymes and production of vitamins and antimicrobial substances; (b) health or sanitary effect which is distinguished by increase in colonisation resistance, competition for gut surface adhesion and stimulation of the immune response.2
Several beneficial functions have been suggested for probiotic bacteria3, e.g.:
  • nutritional benefits
  • vitamin production, availability of minerals and trace elements
  • production of important digestive
  • enzymes (e.g. ß-galactosidase)
  • barrier/restoration effects:
    • infectious diarrhea,
    • antibiotic-associated diarrhea,
    • irradiation-associated diarrhea
  • cholesterol lowering effects
  • stimulation of the immune system
  • enhancement of bowel motility/relief from constipation
  • adherence and colonisation resistance
  • maintenance of mucosal integrity.
Balanced microflora
Probiotic consumption is reported to exert a myriad of beneficial effects including: enhanced immune response, balancing of colonic microbiota, vaccine adjuvant effects, reduction of faecal enzymes implicated in cancer initiation, treatment of diarrhea associated with stress, pH level and antibiotic therapy, control of rotavirus and Clostridium difficile - induced colitis and prevention of ulcers related to Helicobacter pylori.
Imbalanced microflora
Probiotics are also implicated in the reduction of serum cholesterol, the antagonism against food-borne pathogens and tooth decay organisms, the amelioration of lactose malabsorption symptoms as well as candidiasis and urinary tract infections.4
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Bacteria adhesion to digestive tract wall
*FAO/WHO - the Food and Agriculture Organization of the United Nations and the World Health Organization
1. Fioramonti, J., Theodorou, V., Bueno, L. Probiotics: what are they? What are their effects on gut physiology? Best Practice & Research Clinical Gastroenterology, 2003, pp 711–724
2. Anadon, A., Martínez-Larrañaga, M. R., Martinez, M. A. Probiotics for animal nutrition in the European Union. Regulation and safety assessment, Regulatory Toxicology and Pharmacology, 2006, pp 91–95
3. Holzapfel, W. H., Schillinger, U. Introduction to pre- and probiotics, Food Research International Journal, 2002
4. Kaur, I. P., Chopra, K., Saini, A. Probiotics: potential pharmaceutical application, European Journal of Pharmaceutical Sciences , 2002, pp 1–9

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Functional probiotic food for puppies from 5 weeks to 6-9 months of age.

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